
Clinical Studies
With more than a hundred published clinical studies, reviews, numerous case reports and post-marketing clinical surveys, Alpha-Stim® Technology, cranial electrotherapy stimulation (CES) and microcurrent electrical therapy (MET) have been firmly established as safe, effective and highly-cost effective non-pharmacological treatment modalities for anxiety, insomnia, depression and pain.
Please see below for examples of publications on CES and MET in different study-design categories.
Randomized Controlled Trials
Shultz, J. C. (2010). The effects of cranial electrotherapy stimulation on attention: A double-blinded, placebo-controlled investigation. Psy.D. Dissertation. The Chicago School of Professional Psychology, 106 pages.
Strentzsch, J. A. (2009). An examination of cranial electrotherapy stimulation (CES) on alpha-amylase levels, cortisol levels and state-trait anxiety scores in the chronically ill. Doctoral dissertation, Saint Mary’s University, San Antonio, Texas. 121 pages.
Open Label Clinical Trials
Liu Y. and Z. Guiqing (2011). qEEG Study on the Treatment of ADHD with CES. Chinese Journal of Clinicians (Electronic Edition) 5(8):2462-2463.
Mechanistic Studies
Case Series and Case Reports
Plotnick, S. E. (2005). Finding hope: Alpha-Stim® 100 may help clinicians yield better fibromyalgia results. Advance for Directors in Rehabilitation p. 82.
Meta-Analyses, Reviews and Commentaries
Kirsch, D. L. (2006). Why Electromedicine? Practical Pain Management 6(5):52-54.
Kisch, D. L. (2002). The Science Behind Cranial Electrotherapy Stimulation (2nd Ed). Medical Scope Publishing Co., Edmonton, Canada, Pp. 224.
Tutorials
Kirsch, D. L. (2006). Electromedical treatment of headaches. Practical Pain Management, 6(8):58-65.
Kirsch, D. L. (2001). Cranial electrotherapy stimulation: A practical protocol for the treatment of pain. Practical Pain Management 2(3):34-37.